If you’ve been searching for the ultimate comfort food mashup, you’ve hit the jackpot with this Mac and Cheese Meatloaf Casserole Recipe. Imagine the hearty goodness of a classic meatloaf paired with the creamy, cheesy luxury of mac and cheese baked together in one irresistible dish. It’s cosy, satisfying, and surprisingly simple to pull off, making it a perfect go-to for family dinners or casual get-togethers. Each bite brings a nostalgic twist on two beloved favorites, with layers of savory beef and gooey cheese that truly make this casserole a star in your kitchen.

Mac and Cheese Meatloaf Casserole Recipe - Recipe Image

Ingredients You’ll Need

This recipe keeps things straightforward but relies on a handful of classic ingredients that work in harmony to deliver incredible flavor and texture. Every component plays a vital role—from the juicy ground beef laying the meaty foundation to the sharp cheddar cheese that melts into creamy bliss. Let’s break down what you’ll need:

  • 1½ pounds ground beef: The rich, hearty base for your meatloaf that brings robust flavor and satisfying protein.
  • ½ cup breadcrumbs: These help bind the meatloaf together while keeping it tender and moist.
  • 1 large egg: Acts as a natural binder to hold everything firmly in place.
  • ¼ cup ketchup: Adds tangy sweetness to the meatloaf mix for that classic backyard flavor.
  • 1 tablespoon Worcestershire sauce: Deepens the savory notes and adds complexity.
  • 1 teaspoon garlic powder: Infuses a subtle, aromatic punch that complements the beef.
  • 1 teaspoon onion powder: Elevates flavor by bringing mild savory undertones.
  • Salt and black pepper: Essential seasonings to balance and enhance all other flavors.
  • 8 oz elbow macaroni, cooked al dente: The perfect pasta shape to hold all that luscious cheese sauce.
  • 2 tablespoons butter: The foundation of your creamy cheese sauce.
  • 2 tablespoons all-purpose flour: Helps thicken the cheese sauce to just the right consistency.
  • 2 cups milk: Creates the smooth base for the sauce without overpowering.
  • 2 cups shredded sharp cheddar cheese: Delivers bold, melty cheese flavor that defines classic mac and cheese.
  • ½ teaspoon paprika (optional): Adds a gentle smoky warmth and color if you like.
  • Salt and pepper to taste: To season the cheese sauce perfectly.
  • ½ cup extra shredded cheddar cheese: Topping that bakes into a golden, bubbling crust.
  • Chopped parsley or chives for garnish: A fresh, vibrant touch to brighten each serving.

How to Make Mac and Cheese Meatloaf Casserole Recipe

Step 1: Make the Meatloaf Base

Start by preheating your oven to 375°F (190°C). In a large bowl, combine your ground beef, breadcrumbs, egg, ketchup, Worcestershire sauce, garlic powder, onion powder, plus salt and pepper. Mix gently just until everything is blended—overworking can make the meat tough. Press this mixture evenly into a greased 9×13-inch baking dish. Pop it in the oven and bake for 25 minutes. Once done, carefully drain any excess grease to keep your casserole from getting greasy without sacrificing flavor.

Step 2: Prepare Mac and Cheese

While your meatloaf is baking, the magic of the cheese sauce begins. Melt butter in a saucepan over medium heat. Whisk in the flour and cook this roux for about a minute to eliminate any raw flour taste. Gradually add your milk, whisking continuously until the sauce thickens into a smooth, velvety texture. Remove from heat and stir in sharp cheddar cheese until completely melted and creamy. Add cooked macaroni, then season with paprika, salt, and pepper to taste. This rich, cheesy mixture is what makes this casserole truly irresistible.

Step 3: Assemble the Casserole

Once your meatloaf base is ready and still warm, pour the creamy mac and cheese evenly over the top, spreading it out carefully with a spatula. For an extra cheesy finish, sprinkle that reserved half cup of shredded cheddar on top. This layering creates the perfect blend of textures with every forkful, from the firm meatloaf to the luscious cheese and pasta topping.

Step 4: Bake Again

Return your assembled casserole to the oven and bake uncovered for 15 to 20 minutes. Keep an eye on it—the cheese on top should melt into a golden bubbly crust that’s visually inviting and packed with flavor. After baking, give the casserole a little time to rest, about 5 to 10 minutes, which helps everything set nicely for clean slicing.

Step 5: Garnish and Serve

To add a fresh burst of color and a mild oniony note, sprinkle chopped parsley or chives across the top just before serving. This final touch brightens the rich depths of the dish and makes it look as good as it tastes. Gather your loved ones, scoop generous portions, and watch how quickly this crowd-pleaser disappears!

How to Serve Mac and Cheese Meatloaf Casserole Recipe

Mac and Cheese Meatloaf Casserole Recipe - Recipe Image

Garnishes

Fresh herbs like parsley or chives are the perfect finishing touch for this casserole. They add a pop of color along with a subtle freshness that contrasts beautifully with the rich, meaty, and cheesy layers. A light sprinkle of paprika on top can also enhance the overall presentation and flavor with a dash of warmth and color.

Side Dishes

This dish is hearty and filling on its own, but pairing it with bright, crisp side dishes can balance the meal. A simple green salad with a lemon vinaigrette or steamed green beans with garlic makes a lovely accompaniment. For a comforting combo, try roasted vegetables like carrots or broccoli; their natural sweetness complements the savory casserole perfectly.

Creative Ways to Present

If you’re serving guests, consider ramekins or individual portions baked in small dishes for a cute presentation that feels personalized. You can also turn the casserole into scoopable sliders using thick slices layered inside buns for a fun twist. Either way, this Mac and Cheese Meatloaf Casserole Recipe looks stunning when plated with a garnish and a little extra cheese melting on top.

Make Ahead and Storage

Storing Leftovers

After enjoying your casserole, store any leftovers in an airtight container in the refrigerator. It keeps well for about 3 to 4 days without losing too much of its creamy texture or flavor. Just be sure to cool it completely before sealing and refrigerating.

Freezing

This dish freezes nicely if you want to make a big batch in advance. After assembling but before the final bake, cover tightly with foil or plastic wrap and freeze for up to 2 months. When ready to eat, thaw overnight in the fridge, then bake as usual. The texture remains deliciously comforting, making it a great freezer-friendly family meal.

Reheating

Reheat individual portions in the microwave or warm the entire casserole in the oven at 350°F (175°C) for about 20 minutes until hot and bubbly again. To keep the top from drying out, cover loosely with foil during reheating. This way, you get that fresh-baked feel every time.

FAQs

Can I use ground turkey instead of beef?

Absolutely! Ground turkey or even ground chicken are great leaner alternatives. Just be mindful they’re a bit milder, so you might want to add a bit more seasoning to maintain the robust flavor balance.

What’s the best cheese for the mac and cheese sauce?

Sharp cheddar is a classic choice because of its bold flavor and excellent melting qualities. You can mix in some mozzarella or gouda for extra creaminess or a different twist if you prefer.

Can I make this casserole vegetarian?

Yes! Swap the ground beef for a plant-based meat substitute or use cooked lentils and mushrooms to mimic the texture. Adjust seasonings accordingly and you’ll have a satisfying vegetarian version.

Is it necessary to drain the grease after baking the meatloaf base?

Draining excess grease helps prevent the casserole from becoming too oily. However, a little bit of the rendered fat adds flavor, so just remove the excess carefully without rinsing to keep that meaty richness.

How do I know when the casserole is done baking the second time?

Look for a golden, bubbly top and slightly firm edges around the casserole dish. Letting it rest after baking also helps it set and makes slicing easier without falling apart.

Final Thoughts

This Mac and Cheese Meatloaf Casserole Recipe is truly one of those dishes that brings smiles around the table and warms the soul. Whether you’re cooking for a busy weeknight or a cozy weekend feast, it combines comfort, flavor, and ease like very few meals can. Give it a try—you might just find your new favorite way to enjoy two classic dishes at once.

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Mac and Cheese Meatloaf Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.2 from 74 reviews
  • Author: admin
  • Prep Time: 20 minutes
  • Cook Time: 45 minutes
  • Total Time: 1 hour 5 minutes
  • Yield: 6 to 8 servings
  • Category: Casserole
  • Method: Baking
  • Cuisine: American

Description

This Mac and Cheese Meatloaf Casserole combines the comforting flavors of classic meatloaf with creamy macaroni and cheese, all baked together in a single dish. With layers of seasoned ground beef and cheesy mac, topped with melted cheddar and fresh herbs, it’s a hearty and satisfying meal perfect for family dinners or casual gatherings.


Ingredients

Scale

Meatloaf Base

  • 1½ pounds (680g) ground beef
  • ½ cup breadcrumbs
  • 1 large egg
  • ¼ cup ketchup
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • Salt and black pepper, to taste

Mac and Cheese

  • 8 oz (225g) elbow macaroni, cooked al dente
  • 2 tablespoons butter
  • 2 tablespoons all-purpose flour
  • 2 cups (475ml) milk
  • 2 cups shredded sharp cheddar cheese
  • ½ teaspoon paprika (optional)
  • Salt and pepper, to taste
  • ½ cup extra shredded cheddar cheese

Garnish

  • Chopped parsley or chives for garnish


Instructions

  1. Make the Meatloaf Base: Preheat the oven to 375°F (190°C). In a large bowl, combine ground beef, breadcrumbs, egg, ketchup, Worcestershire sauce, garlic powder, onion powder, salt, and black pepper. Mix thoroughly until combined. Press the mixture evenly into a greased 9×13-inch baking dish. Bake for 25 minutes, then carefully drain off any excess grease.
  2. Prepare Mac and Cheese: While the meatloaf is baking, melt butter in a saucepan over medium heat. Whisk in the flour and cook for a minute to form a roux. Gradually pour in milk while whisking constantly to avoid lumps. Continue stirring until the sauce thickens. Remove from heat and stir in shredded cheddar cheese until melted and smooth. Add cooked elbow macaroni, paprika if using, and season with salt and pepper. Mix well to combine.
  3. Assemble the Casserole: Spread the prepared mac and cheese evenly over the baked meatloaf base in the baking dish. Sprinkle the extra shredded cheddar cheese evenly on top if desired.
  4. Bake Again: Return the casserole to the oven and bake uncovered for an additional 15–20 minutes or until the top is golden and bubbly. Once done, remove from oven and let it rest for 5–10 minutes to set before slicing.
  5. Garnish and Serve: Sprinkle chopped parsley or chives over the casserole as a fresh garnish before serving to add color and flavor.

Notes

  • For best results, cook the macaroni just until al dente before mixing into the cheese sauce to prevent overcooking during baking.
  • To reduce grease, use lean ground beef or turkey instead of higher fat content beef.
  • The paprika is optional but adds a nice subtle smoky flavor and color to the cheese sauce.
  • Letting the casserole rest before slicing helps it hold shape and makes serving easier.
  • You can prepare the meatloaf base a day ahead and refrigerate it before baking.

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